Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytokine gene polymorphisms in autoimmune thyroid disease.

The Journal of clinical endocrinology and metabolism - 1 May 2000

Hunt P J, Marshall S E, Weetman A P, Bell J I, Wass J A, Welsh K I

Abstract excerpt

Susceptibility to the autoimmune thyroid diseases, Graves' disease (GD) and autoimmune hypothyroidism (AIH), depends on a complex interaction between environmental and genetic factors. The human leukocyte antigen and cytotoxic T lymphocyte-associated-4 regions appear to influence susceptibility to disease, but the effect is not major, and the other genes remain unknown. Cytokines are crucial in the regulation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Graves Disease
Share to Interleukin-1
Share to Interleukin 1 Receptor Antagonist Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-4

Share to Receptors, Interleukin-1

Share to Receptors, Interleukin-4

Share to Sialoglycoproteins

Share to Thyroiditis, Autoimmune

Source

Identifiers

PMID: 10843185
DOI: 10.1210/jcem.85.5.6588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytokine gene polymorphisms in autoimmune thyroid disease.PMID 10843185Read ↗

Genetic variants of interleukin-4 gene in autoimmune thyroid diseases: an updated meta-analysis.Semantic proximity Read ↗

Association analysis of interleukin gene polymorphisms in autoimmune thyroid diseases in the Tunisian population.Semantic proximity Read ↗

General and Specific Genetic Polymorphism of Cytokines-Related Gene in AITD.Semantic proximity Read ↗

Gene polymorphisms of interleukin-4, interleukin-10 and transforming growth factor-beta in Graves' disease.Semantic proximity Read ↗

Polymorphisms in the TNFA and IL6 genes represent risk factors for autoimmune thyroid disease.Semantic proximity Read ↗

The interleukin-1 family gene polymorphisms and Graves' disease.Semantic proximity Read ↗

Cytokine gene polymorphisms and human autoimmune disease in the era of genome-wide association studies.Semantic proximity Read ↗

Association of cytokine gene polymorphisms (IL6, IL10, TNF-α, TGF-β and IFN-γ) and Graves' disease in Turkish population.Semantic proximity Read ↗

Cytokine gene polymorphisms in multifactorial diseases: gateways to novel targets for immunotherapy?Semantic proximity Read ↗

Association of TNF-alpha, TNF-beta, IFN-gamma and IL-1Ra gene polymorphisms with Graves' disease in the Thai population.Semantic proximity Read ↗

The association of interleukin-1alpha and interleukin-1beta polymorphisms with the risk of Graves' disease in a case-control study and meta-analysis.Semantic proximity Read ↗

Lack of association between pro-inflammatory cytokine (IL-6, IL-8 and TNF-alpha) gene polymorphisms and Graves' disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.