Article
Concerted influence of key amino acids on the lipid binding properties of a single-spanning membrane protein: NMR and mutational analysis.
Biochemistry - 21 Aug 2001
Mousson F, Beswick V, Coïc Y M, Baleux F, Huynh-Dinh T, Sanson A, Neumann J M
Abstract excerpt
Finding the combinations of key amino acids involved in the interaction network underlying the interfacial features of membrane proteins would contribute to a better understanding of their sequence-structure-function relationships and the role of anionic phospholipids. To further address these questions, we performed mutational analysis associated with NMR experiments on synthetic fragments of the single-spanning...
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