Article
Functional manipulation of a calcium-binding protein from Entamoeba histolytica guided by paramagnetic NMR.
The Journal of biological chemistry - 9 Aug 2013
Rout Ashok K, Patel Sunita, Somlata, Shukla Manish, Saraswathi Deepa, Bhattacharya Alok, Chary Kandala V R
Abstract excerpt
EhCaBP1, one of the calcium-binding proteins from Entamoeba histolytica, is a two-domain EF-hand protein. The two domains of EhCaBP1 are structurally and functionally different from each other. However, both domains are required for structural stability and a full range of functional diversity. Analysis of sequence and structure of EhCaBP1 and other CaBPs indicates that the C-terminal domain of EhCaBP1 possesses...
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