Article
Effect of glutathione S-transferase M1 genotype on progression of atherosclerosis in lifelong male smokers.
Atherosclerosis - 1 Sept 2001
de Waart F G, Kok F J, Smilde T J, Hijmans A, Wollersheim H, Stalenhoef A F
Abstract excerpt
We hypothesize that smokers with the null genotype for GSTM1 (GSTM1-0), who thus lack the detoxification enzyme glutathione S-transferase mu-1, develop atherosclerosis at an increased rate compared to smokers with the positive genotype (GSTM1-1). We used data from a 2-year randomized placebo-controlled trial on the effect of vitamin E on atherosclerosis among 189 male smokers. Progression of atherosclerosis was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.