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Article

Risk of atherosclerosis: interaction of smoking and glutathione S-transferase genes.

Epidemiology (Cambridge, Mass.) - 1 May 2003

Olshan Andrew F, Li Rongling, Pankow James S, Bray Molly, Tyroler Herman A, Chambless Lloyd E, Boerwinkle Eric, Pittman Gary S, Bell Douglas A

Abstract excerpt

BACKGROUND: Cigarette smoking is a well-known risk factor for not only incident events of coronary heart disease, but also preclinical atherosclerosis. Enzymes including glutathione S-transferase mu (GSTM1) and theta (GSTT1) are involved in the metabolism of tobacco smoke chemicals and are expressed in human vessels and smooth muscle cells. METHODS: We estimated the effect of interaction of smoking with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12859033

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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