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Article

Glutathione S-transferase gene polymorphism as a susceptibility factor in smoking-related coronary artery disease.

Basic research in cardiology - 1 May 2004

Tamer Lülüfer, Ercan Bahadir, Camsari Ahmet, Yildirim Hatice, Ciçek Dilek, Sucu Nehir, Ateş Nurcan Aras, Atik Uğur

Abstract excerpt

Coronary artery disease (CAD) is the leading cause of morbidity and mortality in the world, and cigarette smoking is a major contributing factor to the disease. Glutathione S-transferase (GST) enzyme is implicated in the detoxification of carcinogens present in tobacco smoke and consequent polymorphisms in this gene may confer susceptibility to cardiovascular disease if DNA damage is important in CAD. Therefore,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15088107
DOI: 10.1007/s00395-004-0465-8

Genes

GSTM1
GSTT1
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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