Article
An updated meta-analysis showed smoking modify the association of GSTM1 null genotype on the risk of coronary heart disease.
Bioscience reports - 26 Feb 2021
Song Yadong, Shan Zhilei, Liu Xiaoli, Chen Xiaomin, Luo Cheng, Chen Liangkai, Wang Yimei, Gong Lin, Liu Liegang, Liang Jiansheng
Abstract excerpt
Background Oxidative stress is considered to be involved in the pathogenesis of coronary heart disease (CHD). Glutathione-S-transferase (GST) enzymes play important roles in antioxidant defenses and may influence CHD risk. The present meta-analysis was performed to investigate the link between glutathione S-transferase M1 (GSTM1) null genotype and CHD and to get a precise evaluation of interaction between GSTM1...
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