Article
Effect of apoE genotype on the hypolipidaemic response to pravastatin in an outpatient setting.
Journal of internal medicine - 1 Jun 2002
Peña R, Lahoz C, Mostaza J M, Jiménez J, Subirats E, Pintó X, Taboada M, López-Pastor A
Abstract excerpt
BACKGROUND: Considerable variability exists in the plasma lipid and lipoprotein response to statin treatment due, in part, to genetic factors. The gene for apolipoprotein E (ApoE) is polymorphic and the different genotypes modulate baseline lipid levels. The objective of the present study was to evaluate the effect of the apoE genotype on the lipoprotein response to pravastatin treatment in an outpatient...
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