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Article

uPA and uPAR contribute to NK cell invasion through the extracellular matrix.

Anticancer research - 1 Jan 2000

Al-Atrash G, Kitson R P, Xue Y, Mazar A P, Kim M H, Goldfarb R H

Abstract excerpt

BACKGROUND: The urokinase plasminogen activator (uPA) system has been implicated in cellular invasiveness of tumor cells and immune cells. Herein we provide evidence for the production by natural killer (NK) cells of both uPA and its receptor (uPAR). MATERIALS AND METHODS: Western blot analysis, RTPCR, casein/plasminogen zymography, and fluorescence microscopy were employed to detect uPA and uPAR on NK cells. NK...

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PMID: 11497249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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