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Article

Characterization of the active sites in decay-accelerating factor.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2001

Kuttner-Kondo L A, Mitchell L, Hourcade D E, Medof M E

Abstract excerpt

Decay-accelerating factor (DAF) is a complement regulator that dissociates autologous C3 convertases, which assemble on self cell surfaces. Its activity resides in the last three of its four complement control protein repeats (CCP2-4). Previous modeling on the nuclear magnetic resonance structure of CCP15-16 in the serum C3 convertase regulator factor H proposed a positively charged surface area on CCP2 extending...

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Identifiers

PMID: 11490001
DOI: 10.4049/jimmunol.167.4.2164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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