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Article

Pharmacological coal tar induces G:C to T:A transversion mutations in the skin of muta mouse.

Pharmacology & toxicology - 1 Jul 2001

Vogel U, Thein N, Møller P, Wallin H

Abstract excerpt

Coal tar is a by-product of the distillation of coal. It consists of a complex chemical mixture of aromatic and aliphatic hydrocabons, with high concentrations of polycyclic aromatic hydrocarbons such as benzo[a]pyrene. We have previously shown that single painting on skin of mice increases the mutation frequency 16 times in murine epidermis cells (Thein et al. 2000). Here, we have determined the mutations by DNA...

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PMID: 11484907
DOI: 10.1034/j.1600-0773.2001.d01-132.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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