Article
A systematic RNA interference screen reveals a cell migration gene network in C. elegans.
Journal of cell science - 1 Dec 2006
Cram Erin J, Shang Hongyu, Schwarzbauer Jean E
Abstract excerpt
Cell migration is essential during embryonic development and tissue morphogenesis. During gonadogenesis in the nematode Caenorhabditis elegans, migration of the distal tip cells forms two U-shaped gonad arms. Malformation results if the distal tip cells stop prematurely or follow an aberrant path, and abnormalities are easily visualized in living nematodes. Here we describe the first comprehensive in vivo RNA...
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