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Article

Employing the one-cell C. elegans embryo to study cell division processes.

Methods in cell biology - 1 Jan 2018

Hattersley Neil, Lara-Gonzalez Pablo, Cheerambathur Dhanya, Gomez-Cavazos J Sebastian, Kim Taekyung, Prevo Bram, Khaliullin Renat, Lee Kian-Yong, Ohta Midori, Green Rebecca, Oegema Karen, Desai Arshad

Abstract excerpt

The one-cell Caenorhabditis elegans embryo offers many advantages for mechanistic analysis of cell division processes. Conservation of key genes and pathways involved in cell division makes findings in C. elegans broadly relevant. A key technical advantage of this system is the ability to penetrantly deplete essential gene products by RNA interference (RNAi) and replace them with wild-type or mutant versions...

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Identifiers

PMID: 29804670
DOI: 10.1016/bs.mcb.2018.03.008
PMCID: PMC6374127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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