Article
Identification of N-acetyltransferase 2 and CYP2C19 genotypes for hair, buccal cell swabs, or fingernails compared with blood.
Therapeutic drug monitoring - 1 Aug 2001
Tanigawara Y, Kita T, Hirono M, Sakaeda T, Komada F, Okumura K
Abstract excerpt
Genotyping of polymorphic drug metabolizing enzymes may be useful to estimate the blood concentration, efficacy, and toxicity of drugs before administration. Blood samples are most generally used for genotyping; however, sampling is invasive and complicated by handling and transport. Therefore, the authors developed genotyping methods using nonblood specimens, and then each genotype was compared with that from...
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