Article
Identification of antisense RNA stem-loops that inhibit RNA-protein interactions using a bacterial reporter system.
Nucleic acids research - 1 Jun 2010
Yano Akiko, Horiya Satoru, Minami Takako, Haneda Eri, Ikeda Makiko, Harada Kazuo
Abstract excerpt
Many well-characterized examples of antisense RNAs from prokaryotic systems involve hybridization of the looped regions of stem-loop RNAs, presumably due to the high thermodynamic stability of the resulting loop-loop and loop-linear interactions. In this study, the identification of RNA stem-loops that inhibit U1A protein binding to the hpII RNA through RNA-RNA interactions was attempted using a bacterial...
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