Article
Fibroblasts in mechanically stressed collagen lattices assume a "synthetic" phenotype.
The Journal of biological chemistry - 28 Sept 2001
Kessler D, Dethlefsen S, Haase I, Plomann M, Hirche F, Krieg T, Eckes B
Abstract excerpt
Fibroblasts are subjected to changes of the mechanical force balance during physiological as well as pathological situations, such as wound healing, development of hypertrophic scars, and fibrogenesis. However, the molecular response and the changes in fibroblast gene expression upon mechanical s...
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