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Article

Is Human Oxoguanine Glycosylase 1 Genetic Variant Successful Even on Oral Squamous Cell Carcinoma?

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2017

Aydemir Levent, Bireller Elif Sinem, Avci Hakan, Boy Metin Zeynep, Deger Kemal, Unur Meral, Cakmakoglu Bedia

Abstract excerpt

BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most widespread cancer types that arise from different sites of oral cavity and has a 5-year survival rate. This study is aimed at investigating the human oxoguanine glycosylase 1 (hOGG1)-Ser326Cys and APE-Asp148Glu polymorphisms of DNA repair genes in OSCC. MATERIALS AND METHODS: We investigated the hOGG1-Ser326Cys and APE-Asp148Glu polymorphisms of...

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PMID: 28448977
DOI: 10.1159/000466702

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