Article
Accessibility of DNA polymerases to repair synthesis during nucleotide excision repair in yeast cell-free extracts.
Nucleic acids research - 15 Jul 2001
Wu X, Guo D, Yuan F, Wang Z
Abstract excerpt
Nucleotide excision repair (NER) removes a variety of DNA lesions. Using a yeast cell-free repair system, we have analyzed the repair synthesis step of NER. NER was proficient in yeast mutant cell-free extracts lacking DNA polymerases (Pol) beta, zeta or eta. Base excision repair was also proficient without Polbeta. Repair synthesis of NER was not affected by thermal inactivation of the temperature-sensitive...
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