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Article

Repair of rDNA in Saccharomyces cerevisiae: RAD4-independent strand-specific nucleotide excision repair of RNA polymerase I transcribed genes.

Nucleic acids research - 15 Mar 1996

Verhage R A, Van de Putte P, Brouwer J

Abstract excerpt

Removal of UV-induced pyrimidine dimers from the individual strands of the rDNA locus in Saccharomyces cerevisiae was studied. Yeast rDNA, that is transcribed by RNA polymerase I(RNA pol I), is repaired efficiently, slightly strand-specific and independently of RAD26, which has been implicated in transcription-coupled repair of the RNA pol II transcribed RPB2 gene. No repair of rDNA is observed in rad1,2,3 and 14...

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Identifiers

PMID: 8604332
DOI: 10.1093/nar/24.6.1020
PMCID: PMC145761

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