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Article

Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta.

The Journal of biological chemistry - 24 Dec 1999

Washington M T, Johnson R E, Prakash S, Prakash L

Abstract excerpt

The yeast RAD30 gene functions in error-free replication of UV-damaged DNA, and RAD30 encodes a DNA polymerase, pol eta, that has the ability to efficiently and correctly replicate past a cis-syn-thymine-thymine dimer in template DNA. To better understand the role of pol eta in damage bypass, we examined its fidelity and processivity on nondamaged DNA templates. Steady-state kinetic analyses of deoxynucleotide...

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Source

Identifiers

PMID: 10601233
DOI: 10.1074/jbc.274.52.36835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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