Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of CCAAT/enhancer-binding protein-beta isoform synthesis by alternative translational initiation at multiple AUG start sites.

Nucleic acids research - 15 Jul 2001

Xiong W, Hsieh C C, Kurtz A J, Rabek J P, Papaconstantinou J

Abstract excerpt

The mRNA of the intronless, single-copy CCAAT/enhancer-binding protein-beta (C/EBPbeta) gene encodes several isoforms that have truncated transcription activation domains. This occurs by the alternative translational initiation (ATI) at multiple AUG start sites. The C/EBPbeta mRNA has four in-frame AUGs and an internal out-of-frame AUG associated with a small open reading frame (sORF). Initiation of translation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to CCAAT-Enhancer-Binding Protein-beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Codon, Initiator

Share to COS Cells

Share to Lipopolysaccharides

Share to Polyribosomes

Share to Protein Biosynthesis

Share to RNA Caps

Source

Open in PubMed Open full text

Identifiers

PMID: 11452034
DOI: 10.1093/nar/29.14.3087
PMCID: PMC55812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of CCAAT/enhancer-binding protein-beta isoform synthesis by alternative translational initiation at multiple AUG start sites.PMID 11452034Read ↗

CCAAT/enhancer binding protein alpha (C/EBPalpha) is an important mediator of mouse C/EBPbeta protein isoform production.Semantic proximity Read ↗

C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.Semantic proximity Read ↗

Differential Control of the CCAAT/Enhancer-binding Protein β (C/EBPβ) Products Liver-enriched Transcriptional Activating Protein (LAP) and Liver-enriched Transcriptional Inhibitory Protein (LIP) and the Regulation of Gene Expression during the Response to Endoplasmic Reticulum StressSemantic proximity Read ↗

Mammalian Alternative Translation Initiation Is Mostly Nonadaptive.Semantic proximity Read ↗

Spliced or Unspliced, That Is the Question: The Biological Roles of XBP1 Isoforms in PathophysiologySemantic proximity Read ↗

Upstream open reading frames: molecular switches in (patho)physiology.Semantic proximity Read ↗

Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated regionSemantic proximity Read ↗

Cell type specific profiling of alternative translation identifies novel protein isoforms in the mouse brainSemantic proximity Read ↗

Enhanced C/EBPα function extends healthspan and lifespan in the African turquoise killifishSemantic proximity Read ↗

Differential utilization of upstream AUGs in the β-secretase mRNA suggests that a shunting mechanism regulates translationSemantic proximity Read ↗

Leaky Scanning and Reinitiation Regulate BACE1 Gene ExpressionSemantic proximity Read ↗

Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.