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Article

Case control and family-based studies of tryptophan hydroxylase gene A218C polymorphism and suicidality in adolescents.

American journal of medical genetics - 8 Jul 2001

Zalsman G, Frisch A, King R A, Pauls D L, Grice D E, Gelernter J, Alsobrook J, Michaelovsky E, Apter A, Tyano S, Weizman A, Leckman J F

Abstract excerpt

The association of suicidality with polymorphism A218C in intron 7 of tryptophan hydroxylase (TPH) gene remains controversial. The aim of this study was to use family-based methods to examine this association in adolescents in order to eliminate the difficulty of sampling a control group from the same ethnic population. Eighty-eight inpatient adolescents who recently attempted suicide were assessed by structured...

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Identifiers

PMID: 11449398
DOI: 10.1002/ajmg.1406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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