Article
Family-based association study of 5-HT(2A) receptor T102C polymorphism and suicidal behavior in Ashkenazi inpatient adolescents.
International journal of adolescent medicine and health - 1 Jan 2000
Zalsman Gil, Frisch Amos, Baruch-Movshovits Ruth, Sher Leo, Michaelovsky Elena, King Robert A, Fischel Tsvi, Hermesh Haggai, Goldberg Pablo, Gorlyn Marianne, Misgav Sagit, Apter Alan, Tyano Sam, Weizman Abraham
Abstract excerpt
UNLABELLED: Suicidal behavior runs in families and is partially genetically determined. Since greater serotonin 5-HT(2A) receptor binding has been reported in postmortem brain and platelets of suicide victims, the 5-HT(2A) receptor gene polymorphism T102C became one of the candidate sites in the study of suicide and impulsive-aggressive traits. However, studies that examined the association of this polymorphism...
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