Article
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010
Vares Maria, Saetre Peter, Deng Hong, Cai Guiqing, Liu Xiehe, Hansen Thomas, Rasmussen Henrik B, Werge Thomas, Melle Ingrid, Djurovic Srdjan, Andreassen Ole A, Agartz Ingrid, Hall Håkan, Terenius Lars, Jönsson Erik G
Abstract excerpt
Different lines of evidence indicate that methylenetetrahydrofolate reductase (MTHFR) functional gene polymorphisms, causative in aberrant folate-homocysteine metabolism, are associated with increased vulnerability to several heritable developmental disorders. Opposing views are expressed considering the possible association between MTHFR and susceptibility for schizophrenia. In order to evaluate if age of onset...
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