Tissue-specific and minor inter-individual variation in imprinting of IGF2R is a common feature of Bos taurus Concepti and not correlated with fetal weight.

doi:10.1371/journal.pone.0059564

Article

Tissue-specific and minor inter-individual variation in imprinting of IGF2R is a common feature of Bos taurus Concepti and not correlated with fetal weight.

PloS one - 1 Jan 2013

Bebbere Daniela, Bauersachs Stefan, Fürst Rainer W, Reichenbach Horst-Dieter, Reichenbach Myriam, Medugorac Ivica, Ulbrich Susanne E, Wolf Eckhard, Ledda Sergio, Hiendleder Stefan

Abstract excerpt

The insulin-like growth factor 2 receptor (IGF2R) is essential for prenatal growth regulation and shows gene dosage effects on fetal weight that can be affected by in-vitro embryo culture. Imprinted maternal expression of murine Igf2r is well documented for all fetal tissues excluding brain, but polymorphic imprinting and biallelic expression were reported for IGF2R in human. These differences have been...

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Tissue-specific and minor inter-individual variation in imprinting of IGF2R is a common feature of Bos taurus Concepti and not correlated with fetal weight.

Abstract excerpt

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