Article
Paternal expression of WT1 in human fibroblasts and lymphocytes.
Human molecular genetics - 1 Dec 1997
Mitsuya K, Sui H, Meguro M, Kugoh H, Jinno Y, Niikawa N, Oshimura M
Abstract excerpt
The Wilms' tumor suppressor gene ( WT1 ) was previously identified as being imprinted, with frequent maternal expression in human placentae and fetal brains. We examined the allele-specific expression of WT1 in cultured human fibroblasts from 15 individuals. Seven of 15 fibroblast lines were heterozygous for polymorphic alleles, and the expression patterns were variable, i.e., equal, unequal or monoallelic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.