Article
Paternal expression of WT1 in human fibroblasts and lymphocytes.
Human molecular genetics - 1 Dec 1997
Mitsuya K, Sui H, Meguro M, Kugoh H, Jinno Y, Niikawa N, Oshimura M
Abstract excerpt
The Wilms' tumor suppressor gene ( WT1 ) was previously identified as being imprinted, with frequent maternal expression in human placentae and fetal brains. We examined the allele-specific expression of WT1 in cultured human fibroblasts from 15 individuals. Seven of 15 fibroblast lines were hete...
Topics
- Adult
- Aged
- Alleles
- Cells, Cultured
- Chromosomes, Human, Pair 11
- DNA-Binding Proteins
- Dinucleotide Repeats
- Female
- Fetus
- Fibroblasts
- Gene Expression Regulation
- Genes, Wilms Tumor
- Genomic Imprinting