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Article

A genetic model of stress displays decreased lymphocytes and impaired antibody responses without altered susceptibility to Streptococcus pneumoniae.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2001

Murray S E, Lallman H R, Heard A D, Rittenberg M B, Stenzel-Poore M P

Abstract excerpt

Stress pathways affect immune function, the most notable of these pathways being activation of the hypothalamic-pituitary-adrenal (HPA) axis. Although HPA activation has generally been relegated to an immunosuppressive role, recent evidence suggests that stress and HPA activation can be immunoenhancing in certain situations. To investigate specific effects of stress on immune function, we used a genetic model of...

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PMID: 11441072
DOI: 10.4049/jimmunol.167.2.691

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CRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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