Article
Stress, glucocorticoids and the susceptibility to develop autoimmune disorders of the central nervous system.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Apr 2001
Morale C, Brouwer J, Testa N, Tirolo C, Barden N, Dijkstra C D, Amor S, Marchetti B
Abstract excerpt
Alterations of the immunoendocrine circuit along the hypothalamic-pituitary-adrenocortical (HPA) axis in various autoimmune diseases have recently been observed, suggesting a modulatory role of this feedback regulation in the pathogenesis of autoimmune diseases. Susceptibility to experimental autoimmune encephalomyelitis (EAE) may be influenced by variations in the production of endogenous glucocorticoid hormones...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
