Article
An animal model for the study of genetic predisposition in the pathogenesis of middle ear inflammation.
The Laryngoscope - 1 Sept 2000
Clark J M, Brinson G, Newman M K, Jewett B S, Sartor B R, Prazma J, Pillsbury H C
Abstract excerpt
OBJECTIVES: Chronic otitis media with effusion (COME) is the most prevalent inflammatory disease in children and is associated with numerous adverse long-term sequelae. Many factors have been associated with an increased risk of developing COME, one of which may be a genetic predisposition to the disease. To study the role that genetics play in the pathogenesis of COME, we used an animal model to compare the...
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