Article
ADP-ribosylation factor 6 delineates separate pathways used by endothelin 1 and insulin for stimulating glucose uptake in 3T3-L1 adipocytes.
Molecular and cellular biology - 1 Aug 2001
Lawrence J T, Birnbaum M J
Abstract excerpt
In 3T3-L1 adipocytes, both insulin and endothelin 1 stimulate glucose transport via translocation of the GLUT4 glucose carrier from an intracellular compartment to the cell surface. Yet it remains uncertain as to whether both hormones utilize identical pathways and to what extent each depends on the heterotrimeric G protein Galphaq as an intermediary signaling molecule. In this study, we used a novel inducible...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.