Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GLUT4 facilitates insulin stimulation and cAMP-mediated inhibition of glucose transport.

Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1992

Lawrence J C, Piper R C, Robinson L J, James D E

Abstract excerpt

The glucose transporter isoform GLUT4 is found only in cells that exhibit insulin-sensitive glucose transport. To investigate the function of this transporter, L6 myoblasts were stably transfected with GLUT4 cDNA. GLUT4 underwent insulin-dependent movement to the cell surface in myoblasts overexpressing the transporter. One cell line (243-6) expressed sufficient levels of the GLUT4 protein to study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Cell Membrane
Share to CHO Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cricetinae

Share to Gene Expression

Share to Insulin

Share to Kinetics

Source

Open in PubMed Open full text

Identifiers

PMID: 1314390
DOI: 10.1073/pnas.89.8.3493
PMCID: PMC48894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GLUT4 facilitates insulin stimulation and cAMP-mediated inhibition of glucose transport.PMID 1314390Read ↗

Canonical and Alternative Pathways (Insulin and Exercise) of GLUT4 Synthesis, Signaling, Intracellular Clustering, and Recruitment to the Plasma MembraneSemantic proximity Read ↗

Reduction of insulin-stimulated glucose uptake in L6 myotubes by the protein kinase inhibitor SB203580 is independent of p38MAPK activity.Semantic proximity Read ↗

Direct demonstration of insulin-induced GLUT4 translocation to the surface of intact cells by insertion of a c-myc epitope into an exofacial GLUT4 domainSemantic proximity Read ↗

Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-lambda on insulin-stimulated glucose transport in L6 myotubes.Semantic proximity Read ↗

Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling.Semantic proximity Read ↗

Biphasic alteration of glucose transport in 3T3-L1 cells during differentiation to the adipocyte-like phenotype.Semantic proximity Read ↗

Myo1c regulates glucose uptake in mouse skeletal muscle.Semantic proximity Read ↗

AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.Semantic proximity Read ↗

ADP-ribosylation factor 6 delineates separate pathways used by endothelin 1 and insulin for stimulating glucose uptake in 3T3-L1 adipocytes.Semantic proximity Read ↗

Platelet-derived growth factor triggers translocation of the insulin-regulatable glucose transporter (type 4) predominantly through phosphatidylinositol 3-kinase binding sites on the receptor.Semantic proximity Read ↗

Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic β-cellsSemantic proximity Read ↗

Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.