Article
GLUT4 facilitates insulin stimulation and cAMP-mediated inhibition of glucose transport.
Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1992
Lawrence J C, Piper R C, Robinson L J, James D E
Abstract excerpt
The glucose transporter isoform GLUT4 is found only in cells that exhibit insulin-sensitive glucose transport. To investigate the function of this transporter, L6 myoblasts were stably transfected with GLUT4 cDNA. GLUT4 underwent insulin-dependent movement to the cell surface in myoblasts overexp...
Topics
- Animals
- Biological Transport
- Bucladesine
- CHO Cells
- Cell Membrane
- Cricetinae
- Cyclic AMP
- Cycloheximide
- Cytochalasin B
- Deoxyglucose
- Gene Expression
- Glucose
- Insulin
- Insulin-Like Growth Factor I
- Kinetics
- L Cells
- Mice
- Monosaccharide Transport Proteins