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Article

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation.

The Journal of biological chemistry - 25 Apr 2003

Sano Hiroyuki, Kane Susan, Sano Eiko, Mîinea Cristinel P, Asara John M, Lane William S, Garner Charles W, Lienhard Gustav E

Abstract excerpt

Insulin stimulates the rapid translocation of intracellular glucose transporters of the GLUT4 isotype to the plasma membrane in fat and muscle cells. The connections between known insulin signaling pathways and the protein machinery of this membrane-trafficking process have not been fully defined. Recently, we identified a 160-kDa protein in adipocytes, designated AS160, that is phosphorylated by the...

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PMID: 12637568
DOI: 10.1074/jbc.C300063200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation.PMID 12637568Read ↗

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