Article
Imprinting of the mouse Igf2r gene depends on an intronic CpG island.
Molecular and cellular endocrinology - 25 May 1998
Wutz A, Barlow D P
Abstract excerpt
Gametic imprinting is a developmental process that uses cis-acting epigenetic mechanisms to induce parental-specific expression in autosomal and X-linked genes. From the limited knowledge we have of imprinted genes it seems clear that they play a role in regulating the growth and development of t...
Topics
- Alleles
- Animals
- CpG Islands
- DNA Methylation
- Female
- Gene Expression Regulation
- Genomic Imprinting
- Insulin-Like Growth Factor II
- Introns
- Male
- Mice
