Article
Imprinting of the mouse Igf2r gene depends on an intronic CpG island.
Molecular and cellular endocrinology - 25 May 1998
Wutz A, Barlow D P
Abstract excerpt
Gametic imprinting is a developmental process that uses cis-acting epigenetic mechanisms to induce parental-specific expression in autosomal and X-linked genes. From the limited knowledge we have of imprinted genes it seems clear that they play a role in regulating the growth and development of the placenta and embryo in utero, and also in the early post-natal phase. The biological function of imprinting in...
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