Article
The imprinting box of the mouse Igf2r gene.
Nature - 7 Jan 1999
Birger Y, Shemer R, Perk J, Razin A
Abstract excerpt
Genomic imprinting is a phenomenon characterized by parent-of-origin-specific expression. The imprint is a mark established during germ-cell development to distinguish between the paternal and maternal copies of the imprinted genes. This imprint is maintained throughout embryo development and erased in the embryonic gonads to set the stage for a new imprint. DNA methylation is essential in this process as shown...
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