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Article

The effect of platelet PlA polymorphism on experimental thrombus formation in man depends on blood flow and thrombogenic substrate.

Thrombosis and haemostasis - 1 Jun 2001

Cadroy Y, Sakariassen K, Grandjean H, Thalamas C, Boneu B, Sié P

Abstract excerpt

A number of studies have reported conflicting data on the association of the PlA1/PlA2 polymorphism of the GPIIIa gene and coronary syndromes. We have investigated the effect of this polymorphism on experimental platelet thrombus formation in man. Forty healthy male volunteers were genotyped for...

Topics

Adult
Blood Flow Velocity
Collagen Type I
Fibrin
Genotype
Humans
Male
Perfusion
Platelet Adhesiveness
Platelet Glycoprotein GPIIb-IIIa Complex
Polymorphism, Genetic
Protein Binding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stress, Mechanical

Thromboplastin

Thrombosis

Source

Identifiers

PMID: 11434691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-11434691-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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