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Article

The effect of platelet PlA polymorphism on experimental thrombus formation in man depends on blood flow and thrombogenic substrate.

Thrombosis and haemostasis - 1 Jun 2001

Cadroy Y, Sakariassen K, Grandjean H, Thalamas C, Boneu B, Sié P

Abstract excerpt

A number of studies have reported conflicting data on the association of the PlA1/PlA2 polymorphism of the GPIIIa gene and coronary syndromes. We have investigated the effect of this polymorphism on experimental platelet thrombus formation in man. Forty healthy male volunteers were genotyped for the PlA1/PlA2 polymorphism. Thrombus formation was induced ex vivo by exposing a tissue factor (TF) or a...

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PMID: 11434691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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