Article
CDKN2A is not the principal target of deletions on the short arm of chromosome 9 in neuroendocrine (Merkel cell) carcinoma of the skin.
International journal of cancer - 1 Aug 2001
Cook A L, Pollock P M, Welch J, Walsh M D, Bowman R V, Baumann K C, Hayward N K, Leonard J H
Abstract excerpt
The majority of small-cell lung cancers (SCLCs) express p16 but not pRb. Given our previous study showing loss of pRb in Merkel cell carcinoma (MCC)/neuroendocrine carcinoma of the skin and the clinicopathological similarities between SCLC and MCC, we wished to determine if this was also the case in MCC. Twenty-nine MCC specimens from 23 patients were examined for deletions at 10 loci on 9p and 1 on 9q. No loss...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
