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Article

Tumor Heterogeneity in Colorectal Cancer: What Do We Know So Far?

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2018

Sagaert Xavier, Vanstapel Arno, Verbeek Sanne

Abstract excerpt

Colorectal cancer is not one disease but rather a collection of neoplastic diseases. Due to heterogeneity in the disease biology, therapy response, and prognosis, extensive disease stratification is required. Therefore, TNM stage, microsatellite status, tumor grade, lymphovascular invasion, and other parameters are assessed in the pathology report to indicate the extent and prognosis of the disease. The mutation...

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Identifiers

PMID: 29414818
DOI: 10.1159/000486721

Genes

BRAF
EGFR
KRAS
NRAS

Provenance

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