Article
Intratumor heterogeneity: A new perspective on colorectal cancer research.
Cancer medicine - 1 Oct 2020
Zheng Zicheng, Yu Tao, Zhao Xinyu, Gao Xin, Zhao Yao, Liu Gang
Abstract excerpt
Colorectal cancers generally consist of multiple subclones. These subclones have their own unique characteristics, resulting in intratumor heterogeneity (ITH). As the discussion of ITH has advanced, a model describing the relationship of ITH to the tumor has gradually emerged. ITH can be divided into two types of intraprimary tumor heterogeneity and intraindividual tumor heterogeneity, the former for further...
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