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Article

Analysis of the open region of RNA polymerase II transcription complexes in the early phase of elongation.

Nucleic acids research - 1 Jul 2001

Fiedler U, Timmers H T

Abstract excerpt

The RNA polymerase II (pol II) transcription complex undergoes a structural transition around registers 20-25, as indicated by ExoIII footprinting analyses. We have employed a highly purified system to prepare pol II complexes stalled at very precise positions during the initial stage of transcript elongation. Using potassium permanganate we analyzed the open region ('transcription bubble') of complexes stalled...

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Identifiers

PMID: 11433015
DOI: 10.1093/nar/29.13.2706
PMCID: PMC55769

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Source receipt: pubmed, retrieved 7 Sept 2026.

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