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Article

DNA melting and promoter clearance by eukaryotic RNA polymerase I.

Journal of molecular biology - 26 May 2000

Kahl B F, Li H, Paule M R

Abstract excerpt

Ribosomal RNA transcription initiation requires the melting of DNA to form an open complex, formation of the first few phosphodiester bonds, commencement of RNA polymerase I movement along the DNA, clearance of the promoter, and the formation of a steady-state ternary elongation complex. We examined DNA melting and promoter clearance by using potassium permanganate, diethylpyrocarbonate and...

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PMID: 10860723
DOI: 10.1006/jmbi.2000.3743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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