Article
Characterization of Na,K-ATPase and H,K-ATPase enzymes with glycosylation-deficient beta-subunit variants by voltage-clamp fluorometry in Xenopus oocytes.
Biochemistry - 8 Apr 2008
Dürr Katharina L, Tavraz Neslihan N, Zimmermann Dirk, Bamberg Ernst, Friedrich Thomas
Abstract excerpt
The role of N-linked glycosylation of beta-subunits in the functional properties of the oligomeric P-type ATPases Na,K- and H,K-ATPase has been examined by expressing glycosylation-deficient Asn-to-Gln beta-variants in Xenopus oocytes. For both ATPases, the absence of the huge N-linked oligosaccharide moiety on the beta-subunit does not affect alpha/beta coassembly, plasma membrane delivery or functional activity...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
