Article
The reovirus S4 gene 3' nontranslated region contains a translational operator sequence.
Journal of virology - 1 Jul 2001
Mochow-Grundy M, Dermody T S
Abstract excerpt
Reovirus mRNAs are efficiently translated within host cells despite the absence of 3' polyadenylated tails. The 3' nontranslated regions (3'NTRs) of reovirus mRNAs contain sequences that exhibit a high degree of gene-segment-specific conservation. To determine whether the 3'NTRs of reovirus mRNAs serve to facilitate efficient translation of viral transcripts, we used T7 RNA polymerase to express constructs...
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