Article
Biosynthesis of reovirus-specified polypeptides: ribosome pausing during the translation of reovirus S1 mRNA.
Virology - 1 Feb 1992
Doohan J P, Samuel C E
Abstract excerpt
The steady-state distribution of translating ribosomes on the reovirus serotype 1 Lang strain polycistronic s1 mRNA and the monocistronic s4 mRNA was mapped using a sensitive primer extension assay and cDNA clones of the S1 and S4 genes. The distribution of translating ribosomes on the reovirus s1 and s4 mRNAs was not uniform. Major positions of ribosome pausing were detected in both rabbit reticulocyte and wheat...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Electrophoresis, Polyacrylamide Gel
- Molecular Sequence Data
- Mutation
- Peptide Biosynthesis
- Precipitin Tests
- Protein Biosynthesis
- RNA, Messenger
- RNA, Viral
