The brefeldin A resistance protein Bfr1p is a component of polyribosome-associated mRNP complexes in yeast.

doi:10.1093/nar/29.12.2567

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Article

The brefeldin A resistance protein Bfr1p is a component of polyribosome-associated mRNP complexes in yeast.

Nucleic acids research - 15 Jun 2001

Lang B D, Li Am, Black-Brewster H D, Fridovich-Keil J L

Abstract excerpt

The yeast gene BFR1 was originally isolated from a genetic screen for high-copy suppressors of brefeldin A-induced lethality in Saccharomyces cerevisiae. While this result suggested a possible role for the encoded protein, Bfr1p, in the secretory pathway, subsequent data have not fully supported this conclusion. Alternatively, Bfr1p has also been found by yeast two-hybrid analysis to interact with Bbp1p, a...

Topics

Brefeldin A
Cell Membrane
Chromatography, Affinity
Chromatography, Gel
Chromosome Segregation
Drug Resistance, Microbial
Endoplasmic Reticulum
Fungal Proteins
Gene Expression
Membrane Proteins
Microscopy, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nuclear Envelope

Nuclear Proteins

Phenotype

Polyribosomes

Protein Binding

Protein Transport

RNA, Fungal

Source

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Identifiers

PMID: 11410665
DOI: 10.1093/nar/29.12.2567
PMCID: PMC55738

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