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Article

Long chain base tolerance in Saccharomyces cerevisiae is induced by retrograde signals from the mitochondria.

The Journal of biological chemistry - 10 Mar 2006

Panwar Sneh Lata, Moye-Rowley W Scott

Abstract excerpt

Saccharomyces cerevisiae cells lacking their mitochondrial DNA (rho0 cells) respond to this loss of genetic information by induction of a program of nuclear gene expression called the retrograde response. Expression of genes involved in multidrug resistance and sphingolipid biosynthesis is coordinately induced in rho0 cells by the zinc cluster transcription factor Pdr3p. In this report, we identify a membrane...

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PMID: 16407254
DOI: 10.1074/jbc.M512115200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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