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Article

Familial aggregation and heritability of ankylosing spondylitis - a Swedish nested case-control study.

Rheumatology (Oxford, England) - 1 Jul 2020

Morin Matilda, Hellgren Karin, Frisell Thomas

Abstract excerpt

OBJECTIVES: AS is known to be a highly heritable disease, but previous studies on the magnitude of the familial aggregation and heritability of AS have been small and inconclusive, with familial relative risks ranging from 17 to 94. We aimed to improve estimates of these factors by studying families of all subjects diagnosed with AS in Sweden over a period of 16 years and to investigate if familial risks vary by...

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Identifiers

PMID: 31687771
DOI: 10.1093/rheumatology/kez519
PMCID: PMC7310084

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