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Article

Susceptibility to ankylosing spondylitis in twins the role of genes, HLA, and the environment

1 Oct 1997

Abstract excerpt

OBJECTIVE: To determine the relative effects of genetic and environmental factors in susceptibility to ankylosing spondylitis (AS). METHODS: Twins with AS were identified from the Royal National Hospital for Rheumatic Diseases database. Clinical and radiographic examinations were performed to establish diagnoses, and disease severity was assessed using a combination of validated scoring systems. HLA typing for...

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PMID: 9336417
DOI: 10.1002/art.1780401015

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