Article
Concordance of disease severity among family members with ankylosing spondylitis?
The Journal of rheumatology - 1 Sept 2004
Brophy Sinead, Hickey Sarah, Menon Ajit, Taylor Gordon, Bradbury Linda, Hamersma Jasmin, Calin Andrei
Abstract excerpt
OBJECTIVE: The heritability of disease activity and function in ankylosing spondylitis (AS) have been estimated at 0.51 and 0.63 (i.e., 51% and 63%), respectively. We examined the concordance of disease severity among family members in terms of disease activity, function, radiological change, prevalence of iritis, and juvenile onset. METHODS: Disease activity and functional impairment due to AS were studied using...
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