Article
Small GTP-binding protein Ral modulates regulated exocytosis of von Willebrand factor by endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2001
de Leeuw H P, Fernandez-Borja M, Reits E A, Romani de Wit T, Wijers-Koster P M, Hordijk P L, Neefjes J, van Mourik J A, Voorberg J
Abstract excerpt
Weibel-Palade bodies are endothelial cell-specific organelles, which contain von Willebrand factor (vWF), P-selectin, and several other proteins. Recently, we found that the small GTP-binding protein Ral is present in a subcellular fraction containing Weibel-Palade bodies. In the present study, w...
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