Mechanisms of protection induced by live attenuated simian immunodeficiency virus

doi:10.1111/j.1600-0684.2001.300101.x

Article

Mechanisms of protection induced by live attenuated simian immunodeficiency virus

1 Feb 2001

Abstract excerpt

In this study, we investigated whether a type of retroviral interference might be one mechanism that mediates the powerful protection induced by live attenuated SIVC8. Our results show that retroviral interference could be demonstrated between SIV and SHIV-HXBc2 in human T-cell lines chronically infected with either SIVC8 or SIVJ5. Lymphocytes from macaques infected with live attenuated SIVC8 were significantly...

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